Research

Research conducted by QSAR Lab is aimed at developing a set of computer tools that enable us to perform, relatively quickly, comprehensive risk assessments of new materials (including nanomaterials) for human health and the environment.

QSAR Lab’s R&D activity focuses on the development of computer-enabled methods and the application of those methods to expand knowledge in the following fields:

• modeling of material properties at the electronic, atomic and mesoscopic levels,
• assessing (eco)toxicity and the end state of materials in the environment,
• understanding the role of the structural properties of materials in inducing responses at the ‘-omic’ level (e. transcriptomic, proteomic, metabolomic etc.),fundamental causes of adverse effects observed under the proposed Adverse Outcome Pathways (AOP),
• explaining the role of biophysicochemical interactions in the mechanism of material toxicity,
• active participation in adapting risk assessment guidelines to the specificity of (nano) materials in the regulatory context.

QSAR Lab participates in the implementation of three international research projects (PATROLS, RiskGONE and NanoSolveIT) financed within the European Union HORIZON 2020 framework.